【摘 要】
：
Three new indole alkaloids,flueindolines A-C (1-3),along with nine known alkaloids (4-12),were isolated from the fruits ofFlueggea virosa (Roxb.ex Willd.) Voigt.Compounds 1 and 2 are two new fused tricyclic indole alkaloids possessing an unusual pyrido[l,
【机 构】
：
Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University,
论文部分内容阅读
Three new indole alkaloids,flueindolines A-C (1-3),along with nine known alkaloids (4-12),were isolated from the fruits ofFlueggea virosa (Roxb.ex Willd.) Voigt.Compounds 1 and 2 are two new fused tricyclic indole alkaloids possessing an unusual pyrido[l,2-a]indole framework,and 3 presents a rare spiro (pyrrolizidinyl-oxindole) backbone.Their structures with absolute configurations were elucidated by means of comprehensive spectroscopic analysis,chemical calculation,as well as X-ray crystallography.Chiral resolution and absolute configuration determination of the known compounds 4,10,and 11 were reported for the first time.The hypothetical biogenetical pathways of 1-3 were herein also proposed.
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