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日前临床上多采用连续冠脉造影来评价急性心肌梗死(AMI)后的侧支建立情况。然而在某些AMI即期,与梗死相关冠脉的灌注区内已存在良好的侧支循环,因此难以对侧支的进一步发展进行准确的评价。对此作者认为,倘若侧支一旦建立,则受血冠脉内压会随之增高,而冠脉内径亦将相继增加,因此测定相应冠脉内径将有助于评估侧支情况。方法研究对象为7例AMI患者(男5例,女2例,均龄64岁)。研究中借助计算机辅助分析系统分别于AMI即期(梗死后6小时内)和后期(梗死后约42天)就其梗死相关冠脉及其侧支循环的相应受血、供血冠脉内径进行测定。除在即期、后期冠脉造影前5分钟含化硝酸甘油0.3mg外,余药均于24小时前停用。
Recently more clinical use of continuous coronary angiography to evaluate the establishment of collateral after acute myocardial infarction (AMI). However, at some AMIs, a good collateral circulation already exists within the perfusion zone of the infarct-related coronary artery, making accurate evaluation of the collateral development difficult. In this regard, the author believes that if the collateral once established, then blood pressure coronary artery will be higher, and coronary artery diameter will also be increased, so the determination of the corresponding coronary artery diameter will help assess the collateral situation. Methods The subjects were 7 AMI patients (5 males and 2 females, mean age 64 years). In the study, the corresponding blood vessels of coronary artery and its collateral circulation and the diameter of blood supply coronary artery were measured by computer-aided analysis system in the AMI phase (within 6 hours after infarction) and in the later period (about 42 days after infarction) respectively . In addition to the current, postcoronary angiography 5 minutes before nitroglycerin 0.3mg, the remaining drugs were discontinued 24 hours ago.