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目的对比分析两种麻醉方式在支气管肿瘤冷冻术中的麻醉效果及不良反应。方法选取2014年2月至2015年1月间收治的54例支气管肿瘤患者,所有患者均行支气管肿瘤冷冻术,采用随机数字表法将患者分为研究组和对照组,每组27例。研究组患者行气管内插管全身麻醉法,对照组患者行静脉镇静加气管内表面麻醉法。观察患者手术前后的心率、血氧饱和度、平均动脉压以及术后出现的不良反应。结果研究组和对照组患者术前心率、血氧饱和度和平均动脉压差异无统计学意义(P>0.05)。对照组患者在冷冻后3、30 min和冷冻完毕时的心率显著快于研究组(P<0.05),对照组在冷冻后3、30 min时的平均动脉压明显高于研究组(P<0.05)。研究组和对照组患者的血氧饱和度差异无统计学意义(P>0.05)。对照组患者不良反应发生率也显著高于研究组(P<0.05)。结论气管内插管全身麻醉相对静脉镇静加气管内表面麻醉法更好,患者发生不良反应更少,值得推广。
Objective To compare and analyze the anesthetic effects and adverse reactions of two anesthesia methods in bronchial neoplasms. Methods Fifty-four patients with bronchogenic carcinoma who were treated between February 2014 and January 2015 were enrolled in this study. All patients underwent bronchial tumor cryosurgery. Patients were divided into study group and control group by random number table method, with 27 cases in each group. Patients in the study group underwent general anesthesia with endotracheal intubation, and patients in the control group received intravenous sedation and endotracheal anesthesia. The heart rate, oxygen saturation, mean arterial pressure and postoperative adverse reactions were observed before and after the operation. Results There were no significant differences in heart rate, oxygen saturation and mean arterial pressure between study group and control group (P> 0.05). The heart rate of the control group was significantly faster than that of the study group at 3,30 min and after freezing (P <0.05), while the mean arterial pressure of the control group at 3 and 30 min after freezing was significantly higher than that of the study group (P <0.05) ). No significant difference was found in the oxygen saturation between study group and control group (P> 0.05). The incidence of adverse reactions in the control group was also significantly higher than that of the study group (P <0.05). Conclusion The endotracheal intubation general anesthesia is better than the intravenous sedation plus tracheal anesthesia, patients with fewer adverse reactions, it is worth promoting.