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简述几种常见药物的新用途,供临床用药参考。 1 甲氧氯普胺(胃复安、灭吐灵)1.1 治疗肾绞痛 黄森龙报道,用甲氧氯普胺20mg,im治疗56例肾绞痛,以5,10,20,30min观察镇痛效果和显效时间。结果:显效43例,有效8例,总有效率91.1％。1.2 治疗产后缺乳 倪天平报道,甲氧氯普胺用于治疗产后缺乳,效果显著。方法:15mg,tid,po,4d后改为10mg,tid,疗程10d。 2 硝苯地平治疗溃疡病 据文献报道,对54例老年溃疡病患者,给硝苯地平(硝苯吡啶)10mg,tid,po另行对症治疗。结果:治疗组总有效率高达98.17％,对照组总有效率79.63％,两组疗效差异显著。游立本报道,用硝苯地平治疗十二指肠溃疡35例,总有效率91.4％。机理:硝苯地平是钙离子拮抗剂,能快速缓解胃肠道平滑肌痉挛,并有较强的扩张血管作用,可促进微循环,使溃疡周围的血液供应得到改善,使胃肠粘膜抵抗和修复能力加强。
A brief description of several new uses of common drugs for clinical reference. 1 metoclopramide (metoclopramide, metoclopramide) 1.1 Treatment of renal colic Huangsen Long reported metoclopramide 20mg, im treatment of 56 cases of renal colic to observe the analgesic 5,10,20,30 min Effect and effective time. Results: 43 cases markedly effective in 8 cases, the total effective rate was 91.1%. 1.2 treatment of postpartum Ni Deficiency Reported that metoclopramide treatment of postpartum lack of milk, the effect is significant. Methods: 15mg, tid, po, 4d later changed to 10mg, tid, treatment 10d. 2 nifedipine treatment of ulcer disease reported in the literature, 54 cases of elderly patients with ulcer, nifedipine (nifedipine) 10mg, tid, po otherwise symptomatic treatment. Results: The total effective rate was 98.17% in the treatment group and 79.63% in the control group, with significant difference between the two groups. Youli this report, nifedipine treatment of duodenal ulcer in 35 cases, the total effective rate of 91.4%. Mechanism: Nifedipine is a calcium antagonist, can quickly relieve gastrointestinal smooth muscle spasm, and a strong dilatation of blood vessels, can promote microcirculation, the blood supply around the ulcer can be improved, so that gastrointestinal mucosal resistance and repair Ability to strengthen.