论文部分内容阅读
ZES又名胰源性溃疡,促胃泌素瘤,由Zol(?)nger和Ellison于(1955年)首先报告。ZES并非十分少见。据统计,迄今文献中报告证实为本征者已超过2000例。惟国内报告尚少。本文仅就有关ZES的几个方面作一综述。一、病因早在1948年,Poth等根据动物实验提出,胰腺的内分泌和外分泌可能与溃疡病发病有关,后来,Sailer等先后发表了非功能性胰岛细胞瘤伴发消化性溃疡的病例报告。1956年,Zollinger和Ellison报告2例患者具有:(1)严重的消化性溃疡;(2)胃分泌过多;(3)胰腺非β细胞瘤等征候。并首次提出
ZES, also known as pancreatic ulcer, gastrin-stimulating tumor, was first reported by Zol(n)nger and Ellison (1955). ZES is not very rare. According to statistics, the reports in the literature so far have confirmed that there are more than 2000 cases. However, there are few domestic reports. This article only summarizes several aspects related to ZES. First, the cause of the disease as early as 1948, Poth, etc. According to animal experiments suggested that the endocrine and exocrine pancreas may be related to the incidence of ulcer disease, later, Sailer has published a report of non-functional islet cell tumor associated with peptic ulcer cases. In 1956, Zollinger and Ellison reported that 2 patients had: (1) severe peptic ulcer; (2) excessive gastric secretion; (3) non-beta cell tumor of the pancreas and other signs. And first proposed