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目的:观察重组人干扰素α-2b凝胶联合卡介菌多糖核酸治疗扁平疣的临床疗效。方法:选取从2013年5月至2015年5月在我院接受治疗的80例扁平疣患者,将其随机均分为观察组和对照组,每组40例。对照组使用卡介菌多糖核酸治疗,观察组在此基础上联合重组人干扰素α-2b凝胶,观察比较两组的临床疗效和不良反应情况。结果:观察组患者的治疗总有效率为95.0%,对照组为82.5%,组间比较,差异具有统计学意义(P<0.05);观察组不良反应出现率为10.0%,对照组为22.5%,组间比较,差异具有统计学意义(P<0.05)。结论:重组人干扰素α-2b凝胶联合卡介菌多糖核酸治疗扁平疣疗效显著,不良反应发生率较低。
Objective: To observe the clinical efficacy of recombinant human interferon α-2b gel combined with BCG polysaccharide nucleic acid in the treatment of flat warts. Methods: 80 patients with flat warts who were treated in our hospital from May 2013 to May 2015 were randomly divided into observation group and control group, 40 cases in each group. The control group was treated with BCG-PSN. The observation group was combined with recombinant human interferon α-2b gel to observe and compare the clinical efficacy and adverse reactions of the two groups. Results: The total effective rate was 95.0% in the observation group and 82.5% in the control group, the difference was statistically significant (P <0.05); the incidence of adverse reactions was 10.0% in the observation group and 22.5% in the control group , The difference between groups was statistically significant (P <0.05). Conclusion: Recombinant human interferon α-2b gel combined with BCG polysaccharide nucleic acid treatment of flat warts significant effect, the incidence of adverse reactions is low.