rn壬基酚(NP)作为一种环境内分泌干扰物,是目前最常见的工业毒物和环境毒物。NP被排放到自然界中,对生态环境以及生物生存构成威胁。NP进入机体后会造成多种器官系统的损害。本文就当前NP对子代影响的研究进展进行总结,评估NP通过雌激素效应或毒性作用对子代生殖、免疫和神经等系统的损害,为限制这类化合物的使用提供依据。“,”Nonylphenol(NP)as an environmental endocrine disrupter(EEDs)is the most common industrial toxicant and environmental pollutant,which once discharged into natural world,it will pose a threat to ecological environment and biological survival.This review will summarize the research progress of the effects of NP on offspring of animals,and evaluates the impacts of NP on the reproductive,immune and nervous systems of rat offspring in order to provide a theoretic basis for confining the use of such kind of compounds.