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目的了解2011年-2015年某三甲医院鲍曼不动杆菌耐药率及检出率变迁,为医院防控鲍曼不动杆菌及合理用药提供指导。方法对某三甲医院2011年-2015年临床分离的1 343株鲍曼不动杆菌耐药率、耐碳青酶烯鲍曼不动杆菌(CRAB)检出率、科室分布及感染患者检出情况进行分析。结果鲍曼不动杆菌对环丙沙星、亚胺培南、氨苄西林/舒巴坦耐药率逐年提高,对其他常见抗菌药物2015年较2011年均有明显提升;CRAB检出率有逐年升高的趋势,2015年为67.2%;主要分布在重症监护病房。结论随着鲍曼不动杆菌对常用抗菌药物耐药率的增加,CRAB检出率逐年增加,应加强医院感染控制,规范抗菌药物使用,谨防CRAB感染率的增加。
Objective To understand the change of drug resistance rate and detection rate of Acinetobacter baumannii in a top three hospital from 2011 to 2015 and provide guidance for the prevention and control of Acinetobacter baumannii and rational drug use in the hospital. Methods A total of 1 343 strains of Acinetobacter baumannii clinically isolated from a top-three hospital in 2011-2015 were detected, the detection rate of CAB-resistant Acinetobacter baumannii (CRAB) Analyze. Results Acinetobacter baumannii showed an increasing rate of resistance to ciprofloxacin, imipenem and ampicillin / sulbactam year by year, with a significant increase in other common antibacterials compared with 2011 in 2011. The detection rate of CRAB was year by year Rising trend in 2015 to 67.2%; mainly distributed in the intensive care unit. Conclusion As Acinetobacter baumannii increases the rate of resistance to common antibiotics, the detection rate of CRAB has been increasing year by year. It is necessary to strengthen the control of nosocomial infections and standardize the use of antimicrobial agents, so as to prevent the increase of CRAB infection rate.