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目的:观察胃癌术后早期肠内营养支持临床效果。方法:45例胃癌术后患者随机分为两组:肠内营养(enteral nutrition,EN)组和完全胃肠外营养(total parenteral nutrition,TPN)组,分别为23、22例。EN组手术后24h内经空肠近端营养管输注液体肠内营养制剂能全力(NutrisonFibre),TPN组经锁骨下中心静脉静滴,共7d。结果:两组患者术后体重均较术前略低(P<0.01),但组间比较差异无统计学意义。两组总淋巴细胞计数、CD4+/CD8+营养支持前后差异无统计学意义,总蛋白、白蛋白组间比较差异无统计学意义。谷丙转氨酶、总胆红素及直接胆红素组间比较差异无统计学意义。EN组较TPN组肠功能恢复快,排便时间早(P<0.01),平均住院费用低。伤口愈合情况、住院天数差异无统计学意义(P>0.05)。结论:胃癌患者术后早期行肠内营养有利于肠功能恢复,住院费较低,易为患者接受。
Objective: To observe the clinical effect of early postoperative enteral nutrition support for gastric cancer. Methods: Forty-five patients with gastric cancer were randomly divided into two groups: enteral nutrition group and total parenteral nutrition group, with 23 and 22 cases respectively. In EN group, NutrientFibre was infused via the proximal jejunal feeding tube and the TPN group was intravenously dripped into the subclavian vein for 24 hours. Results: The postoperative body weight of both groups was slightly lower than that before operation (P <0.01), but there was no significant difference between the two groups. Total lymphocyte count, CD4 + / CD8 + nutrition support before and after the two groups showed no significant difference, no significant difference was found between total protein and albumin. Alanine aminotransferase, total bilirubin and direct bilirubin no significant difference between the groups. The EN group had faster recovery of bowel function, shorter defecation time (P <0.01) and lower average hospitalization cost than the TPN group. Wound healing, hospitalization days was no significant difference (P> 0.05). Conclusion: The early postoperative enteral nutrition in patients with gastric cancer is conducive to intestinal function recovery, hospitalization costs are low, easy for patients to accept.