目的探讨甲亢合并周期性麻痹临床诊治措施。方法回顾分析30例患者的临床资料。结果本组30例均予以正规抗甲亢治疗,随访6个月～1年,未见复发。结论 TPP的治疗关键在于及时纠正低血钾,在补钾同时要注意控制甲亢,对重症TPP患者或不能口服补钾者,需静脉补钾,应严密观察血钾、尿量变化或做心电图监测。同时应注意避免饱餐、感染、过度劳累、静脉输入高渗葡萄糖等诱发因素。 Objective To investigate the clinical diagnosis and treatment of hyperthyroidism complicated with periodic paralysis. Methods The clinical data of 30 patients were retrospectively analyzed. Results The group of 30 patients were treated with formal anti-hyperthyroidism, followed up for 6 months to 1 year, no recurrence. Conclusions The key point of TPP treatment is to correct hypokalemia promptly. At the same time, we should pay attention to controlling hyperthyroidism while supplementing potassium. For patients with severe TPP or those who can not take oral potassium, we need intravenous potassium. We should closely observe the change of serum potassium and urine or do electrocardiogram monitoring . At the same time should pay attention to avoid eating, infection, over exertion, intravenous infusion of hypertonic glucose and other triggers.