目的建立一种快速有效的尿中锰含量的石墨炉原子吸收光谱测定方法。方法用基体改进剂0.1%PdCl2/0.5%TritonX-100/1%HNO3对尿样稀释后直接采用塞曼-石墨炉原子吸收光谱法测定尿中锰含量。结果该法尿中锰含量在0～10μg/L范围内线性良好,r=0.999 4,最低检出量为0.014μg/L,两个不同锰浓度的尿样的精密度为4.23%和3.95%,不同浓度样品加标回收率在97.5%～106.0%之间。结论该法是快速、简便、灵敏、准确可靠的尿中锰含量检测方法。 Objective To establish a rapid and effective method for the determination of manganese in urine by graphite furnace atomic absorption spectrometry. Methods The urine samples were diluted with 0.1% PdCl2 / 0.5% TritonX-100/1% HNO3 and the content of manganese in the urine was determined directly by Zeeman-graphite furnace atomic absorption spectrometry. Results The urinary manganese content in the range of 0 ~ 10μg / L was linear, r = 0.999 4, the lowest detection was 0.014μg / L. The precision of two different manganese concentrations was 4.23% and 3.95% The spiked recoveries of different concentration samples ranged from 97.5% to 106.0%. Conclusion The method is rapid, simple, sensitive, accurate and reliable detection of urinary manganese content.