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自从 Koehler 和 Milstein 首次成功地将小鼠骨髓瘤细胞和免疫脾细胞进行融合,产生杂交瘤,并分泌出大量的高特异性、纯一的抗——单克隆抗体(monoclonal antibody.McAb)以来,单克隆抗体已广泛用于生物医学的各个
Since the first time that Koehler and Milstein successfully fused mouse myeloma cells with immune spleen cells to produce hybridomas and secreted a large amount of highly specific, pure anti-monoclonal antibody (monoclonal antibody. McAb), Monoclonal antibodies have been widely used in various biomedical applications