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近年来,随着合并能够抑制艾滋病毒生命周期不同阶段关键酶种药物的高度活性抗逆病毒疗法即俗称为“鸡尾酒疗法”的推广应用,艾滋病毒感染所致艾滋病的发病率和死亡率都有相当减少。不过,需予强调的是,高度活性抗逆病毒疗法在具体实践中须特别注意耐药性发展问题,后者会致临床失败并对日后继续治疗造成困难。而避免耐药性发展的一个主要方面就是要求患者有近乎完美的依从性,但此又常常受到药物毒性、
In recent years, with the combination of highly active anti-retroviral therapy that can inhibit key enzyme drugs in different stages of the life cycle of HIV, commonly known as “cocktail therapy”, the incidence and mortality of AIDS caused by HIV infection Have a considerable reduction. However, it is emphasized that in practice, highly active antiretroviral therapy requires special attention to the issue of drug resistance development, which will lead to clinical failure and cause difficulties in continuing treatment in the future. One of the main aspects of avoiding the development of drug resistance is to require that patients have near-perfect compliance, but this is often followed by drug toxicity,