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目的观察连续性血液净化治疗老年急性肾功能衰竭的效果。方法选择老年急性肾功能衰竭患者80例,随机分为观察组和对照组各40例;观察组采用连续性血液净化治疗,对照组采用间歇性血液净化治疗,观察两组治疗前及治疗后7、14、30d时的血肌酐(SCr)及尿素氮(BUN)水平,记录透析过程中并发症及死亡情况。结果两组治疗后BUN及SCr水均较治疗前明显降低(P均﹤0.05),与对照组比较,治疗组降低的更显著(P均﹤0.05)。观察组发生导管栓塞、插管部位感染各3例,消化道出血、心律失常各2例;对照组分别为6、5、4、4例;观察组并发症发生为25.0%,显著低于对照组的47.5%,P﹤0.05。观察组死亡12例,存活28例,病死率为30.0%;对照组分别为17、23例及42.5%;两组病死率比较,P﹤0.05。结论连续性血液净化治疗老年急性肾衰竭肾功能改善快,并发症少,病死率低。
Objective To observe the effect of continuous blood purification on senile acute renal failure. Methods 80 elderly patients with acute renal failure were randomly divided into observation group and control group, 40 cases in each group. The observation group was treated with continuous blood purification, while the control group was treated with intermittent blood purification. , Serum creatinine (SCr) and blood urea nitrogen (BUN) levels at 14 and 30 days. The complication and death during dialysis were recorded. Results The BUN and SCr water levels in both groups were significantly lower than those before treatment (P <0.05). Compared with the control group, the BUN and SCr water levels in the two groups were significantly lower (all P <0.05). In the observation group, there were 3 cases of catheter embolism and intubation, 2 cases of gastrointestinal bleeding and arrhythmia, respectively. The control group were 6, 5, 4 and 4 cases respectively. The incidence of complications in the observation group was 25.0%, which was significantly lower than that of the control group 47.5% of the group, P <0.05. In the observation group, 12 patients died and 28 patients survived. The case fatality rate was 30.0%. In the control group, they were 17,23 and 42.5% respectively. The mortality rates in the two groups were significantly lower than those in the control group (P <0.05). Conclusion Continuous blood purification for the treatment of acute renal failure in elderly patients with improved renal function, fewer complications, low mortality.