疑难病例是临床病理诊断中的一大难题,虽经多方会诊,其结果各家诊断不一,给临床治疗带来一定困难和盲目性。因此迫切需要有更多的客观指标来解决诊断中的分歧。近年来,免疫组化技术的发展,尤其在鉴别诊断上的应用受到了普遍关注。我们搜集了本院及外院会诊疑难病例,进行免疫组化标记,在鉴别诊断中进行探讨。 Difficult cases are a major problem in clinicopathological diagnosis. Although they are diagnosed by multiple parties, the results differ from one to the other, which brings certain difficulties and blindness to clinical treatment. Therefore, there is an urgent need for more objective indicators to resolve the differences in diagnosis. In recent years, the development of immunohistochemistry, especially in differential diagnosis, has received widespread attention. We collected difficult cases in our hospital and in the external hospitals and conducted immunohistochemical markers to discuss the differential diagnosis.