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番泻叶为瓦科植物狭叶番泻Cassia angustifolia Vahl或尖番泻Cassia acutifolia Deljle的干燥叶。中医认为番泻叶具有泻热行滞,通便利水的作用。临床采用沸水泡服的方法来治疗因热结积滞,便秘腹痛,水肿胀满所引起的疾病。近代药理学研究证明番泻叶其泻下的有效成分,主要是番泻甙A、B、C、D以及大黄酸葡萄糖甙和大黄酚等。本文则参照《中国药典》1985年版的方法,以总番泻甙为指标,通过两种不同的浸出方法和时间对番泻叶进行含量测定,比较两种方法对有效成份的影响。
Senna is the dry leaf of the Waco plant Cassia angustifolia Vahl or Cassia acutifolia Deljle. Chinese medicine believes that senna has diarrhea and delays the passage of water. Clinically, a method of boiling water is used to treat diseases caused by heat cramps, constipation, abdominal pain, and swelling. Modern pharmacological studies have demonstrated that the active components of senna sphagnum are senna, A, B, C, D, rhein glucoside, and chrysophanol. This article refers to the “Chinese Pharmacopoeia” 1985 version of the method, the total diarrhea as an indicator, through two different methods and time of leaching senna leaf content determination, compare the effect of the two methods on the effective ingredients.