目的探讨早产脑损伤患儿并发脑性瘫痪的影响因素,为降低早产脑损伤患儿并发脑性瘫痪的发生率提供参考依据。方法选择2013年10月-2014年10月中国人民解放军陆军总医院收治的97例早产脑损伤患儿,收集所有患儿影像学资料(CT及MRI),填写《基本情况调查表》及《母婴围生期基本情况调查表》。由眼科医师检查患儿有无斜视。测定3个月康复训练后患儿大运动进步速度。观察并记录患儿头围、肌张力。对脑损伤早产儿进行跟踪随访调查,采用Logistic回归分析法分析早产脑损伤患儿并发脑性瘫痪的危险因素。结果 97例早产脑损伤患儿中,54例患儿确诊为脑性瘫痪,发生率为55.67%。脑性瘫痪患儿的影像学改变主要为脑室周围白质软化症及弥漫性大脑发育不良。多因素分析显示:斜视、肌张力≥Ⅰ+级、出生体重<2 500 g、有既往妊娠及分娩史、头围<正常值是早产脑损伤患儿并发脑性瘫痪的危险因素(P<0.05)。结论加强围生期保健,定期对早产脑损伤患儿进行脑性瘫痪评估,排查高危患儿,早发现、早治疗,可降低脑性瘫痪的发生率。 Objective To investigate the influencing factors of cerebral palsy in children with premature brain injury and provide a reference for reducing the incidence of cerebral palsy in children with premature brain injury. Methods From October 2013 to October 2014, 97 children with premature brain injury were enrolled in the PLA General Hospital of PLA, all the children were enrolled in the imaging information (CT and MRI), and the “Basic Questionnaire” and “Mother Baby perinatal basic situation questionnaire. ” Ophthalmologist check children with or without strabismus. Determination of 3 months after rehabilitation training in children with large motor speed of progress. Observation and record of children with head circumference, muscle tone. The follow-up investigation of premature infants with brain injury was conducted. Logistic regression analysis was used to analyze the risk factors of cerebral palsy in children with premature birth brain injury. Results Of 97 children with premature brain injury, 54 patients were diagnosed as cerebral palsy, the incidence was 55.67%. Imaging changes in children with cerebral palsy mainly periventricular leukomalacia and diffuse brain dysplasia. Multivariate analysis showed that: strabismus, muscle tone ≥ Ⅰ + grade, birth weight <2500 g, with previous pregnancy and childbirth history, head circumference