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对50例以静脉注射方式的海洛因滥用者(IntrovenousDrugAbusers,IVDAs)和20例经呼吸道(烫吸)吸入的海洛因滥用者(InhaleDrugAbusers,IHDAs)进行了艾滋病病毒抗体(HIVAb)、丙肝病毒抗体(HCVAb)、EB病毒抗体(EBVIgG/Z)和乙肝表面抗原(HBsAg)的血清学检测,并对两个群体的病毒感染状况进行了病例对照研究。结果表明,静脉注射的药物滥用方式是HCV和HBV(丙肝和乙肝病毒)感染的高度危险因素;而非注射方式的药物滥用与HCV、HBV感染似无联系,但是EBV感染的高度危险因素。由于HIV、HBV、HCV都主要是经血行感染,传播途径基本相同,因此,静脉内注射方式的毒品滥用是包括HIV感染在内的HBV、HCV感染的重要独立危险因素。
HIV antibody (HIVAb), hepatitis C virus antibody (HCVAb) and hepatitis C virus (HIV) were tested in 50 cases of intravenous injection of Introvenous Drug Abusers (IVDAs) and 20 cases of Inhaled Drug Abusers (IHDAs) , Epstein-Barr virus (EBVIgG / Z) and hepatitis B surface antigen (HBsAg) serological detection, and two groups of cases of viral infection were case-control study. The results showed that intravenous drug abuse was a high risk factor for HCV and HBV infection (hepatitis C and HBV); non-injectable drug abuse was not associated with HCV and HBV infection but was a high risk factor for EBV infection. Since HIV, HBV and HCV are mainly transmitted by bloodstream and transmitted in basically the same way, drug abuse by intravenous injection is an important independent risk factor for HBV and HCV infection, including HIV infection.