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目的:研究男性不育与染色体异常的关系。方法:对221例男性不育患者进行染色体核型分析和精液常规检测。结果:221例不育男性中,染色体异常发生率为14.0%(31/221),其中性染色体异常占10.9%(24/221),常染色体异常占3.1%(7/221)。结论:染色体异常是造成男性不育重要因素,尤其是无精、少精、弱精症患者,有必要进行细胞遗传学检查。
Objective: To study the relationship between male infertility and chromosomal abnormalities. Methods: 221 cases of male infertility chromosome karyotype analysis and routine testing of semen. Results: Of the 221 infertile men, the incidence of chromosomal abnormalities was 14.0% (31/221), of which 10.9% (24/221) were sex chromosome abnormalities and 3.1% (7/221) were autosomal abnormalities. Conclusion: Chromosomal abnormalities are the important factors causing male infertility, especially in patients with azoospermia, oligospermia and asthenospermia. It is necessary to conduct cytogenetic examination.