生物还原药物的研究是在对肿瘤组织中还原酶的深人研究基础上发展起来的。其中特别是对DT黄递酶（DTh）与肿瘤治疗关系的研究，对此类药物的发展起了重要作用。DTD是双电子还原酶，具有广泛的底物特异性，它与硝基咪吐、氮氧化物及配类药物的代谢有直接关系。生物还原药物被还 Research on bioreductive drugs is based on the deep research of reductase in tumor tissues. Among them, studies on the relationship between DT-diaphorase (DTh) and tumor therapy have played an important role in the development of these drugs. DTD is a dual-electron reductase with a wide range of substrate specificities. It is directly related to the metabolism of nitromidotoxin, nitrogen oxides, and ligand drugs. Bioremediation drugs are also returned