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对寄生线虫进行种群结构和多态性的基因分析,有助于理解抗蠕虫剂治疗后所出现的抗药性表型。作者从捻转血矛线虫体内分离出一种与Tcl类似的转座子Hctcl,研究地理起源不同的种群对化学疗法和近亲交配有抵抗性的Hctcl插入位点的基因多态性。
Genetic analysis of the parasitoid nematode population structure and polymorphism helps to understand the emergence of resistant phenotypes after anthelmintic treatment. The authors isolated a Tcl-like transposon Hctcl from H. contortus to study the genetic polymorphisms of Hctcl insertion sites that are resistant to chemotherapy and inbreeding in populations of different origins.