抗肿瘤药物的寻找为当今药学工作者的重要任务.有关文献较多,并且分散在各种不同的杂志中.为了及时掌握国内外有关方面的研究动态,作者等将有关新抗肿瘤药寻找中合成药方面的材料(自1962年10月到1963年10月),加以分类归纳,以供有关工作者参考.一、烷化剂1963年“肿瘤化学治疗报告”中,Bratzel,Huntress及Goodridge等综述了以往合成的各类氮芥、硫芥、环氧乙烷、环硫化物(episulfides)和乙撑亚胺.在美国的“肿瘤 The search for anti-cancer drugs is an important task of the current pharmacy workers.Related literature is more, and scattered in a variety of different magazines.In order to keep abreast of relevant research at home and abroad, the author will be looking for new antineoplastic agents Synthetic drug materials (from October 1962 to October 1963), to be classified and summarized for reference for the workers .One, alkylating agent 1963 “Cancer Chemotherapy Report”, Bratzel, Huntress and Goodridge, etc. In the past, the synthesis of various nitrogen mustards, sulfur mustards, ethylene oxide, episulfides and ethyleneimine were reviewed. In the United States,