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目的探讨顺铂联合吉西他滨治疗胆囊癌的临床效果。方法选取晚期胆囊癌患者30例,将其根据随机抽签原则分为治疗组与对照组各15例,对照组患者给予顺铂注射液治疗,治疗组患者在对照组治疗基础上给予吉西他滨治疗。结果经治疗后,治疗组患者总有效率为86.7%,对照组患者总有效率为66.7%,差异有统计学意义(P<0.05)。治疗组患者的生理功能、生理职能、躯体疼痛与活力评分明显高于对照组,差异有统计学意义(P<0.05)。结论顺铂联合吉西他滨进行化疗治疗胆囊癌能有效改善患者预后,提高其生活质量。
Objective To investigate the clinical effect of cisplatin combined with gemcitabine in the treatment of gallbladder cancer. Methods Thirty patients with advanced gallbladder cancer were selected and randomly divided into treatment group and control group according to the principle of random sampling. 15 patients in the control group received cisplatin injection. The patients in the treatment group were treated with gemcitabine on the basis of the control group. Results After treatment, the total effective rate was 86.7% in the treatment group and 66.7% in the control group, the difference was statistically significant (P <0.05). Physiological function, physical function, physical pain and vitality scores of the treatment group were significantly higher than those of the control group, the difference was statistically significant (P <0.05). Conclusion Cisplatin combined with gemcitabine in the treatment of gallbladder cancer can effectively improve the prognosis of patients and improve their quality of life.