由于抗生素的广泛应用,风湿性主动脉瓣关闭不全(AI)的发病率已显著下降。相反,随着老龄人口的增加及医学检查手段的进步,非风湿性AI的检出率越来越高。目前,已在临床上占有较重要的地位。本文就其病因及诊断方面的一些问题作一概述。一、病因:AI可由二种主要机制之一引起,即主动脉瓣膜本身的病变与主动脉根部或瓣环的扩张, Due to the widespread use of antibiotics, the incidence of rheumatic aortic regurgitation (AI) has dropped significantly. On the contrary, with the increase of the aging population and the progress of medical examination, the detection rate of non-rheumatic AI is getting higher and higher. At present, it occupies a more important position in the clinic. This article gives an overview of some of its causes and diagnoses. First, the cause: AI can be caused by one of the two main mechanisms, that is, the aortic valve disease and the aortic root or annulus expansion,