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本文报告肺癌高危人群592人7年随访结果。痰检发现支气管上皮细胞中或重度非典型增生组肺癌发病率为正常组的2.31倍,轻度增生组为正常组的1.30倍;对3组的群体特征与肺癌组进行了比较分析,在人群维生素A的含量以肺癌组最低,且发癌后比发癌前有降低趋势,当补充维甲类药后有抑癌作用,3年服药后的抑癌率为75.69％,停药4年后抑癌率为69.70％。
This article reports the results of a 7-year follow-up of 592 people at high risk of lung cancer. The examination revealed that the incidence of lung cancer in the bronchial epithelial cells or severe atypical hyperplasia group was 2.31 times that of the normal group, and that of the mild hyperplasia group was 1.30 times that of the normal group; the population characteristics of the three groups were compared with those of the lung cancer group and were analyzed in the population. The content of vitamin A is the lowest in the lung cancer group, and it tends to be lower than that before the cancer. When the vitamin A is added, it has a tumor suppressing effect. After 3 years of medication, the tumor suppressing rate is 75.69%. After 4 years of withdrawal, the vitamin A content is lower. The tumor suppressor rate was 69.70%.