目的了解重型肝炎患者外周血单核细胞、中性粒细胞、血小板功能与形态改变及其在重型肝炎发病过程中的作用和意义。方法应用血细胞分析法、Born法、ELISA法、放射免疫分析法、免疫荧光法、体外细胞分离培养法、双抗体夹心法、PCR扩增和电镜等技术,对重型肝炎患者外周血单核细胞、中性粒细胞、血小板功能与形态进行系列研究。 Objective To understand the function and morphological changes of peripheral blood mononuclear cells, neutrophils, platelets and their roles in the pathogenesis of severe hepatitis in patients with severe hepatitis. Methods Hematological analysis, Born method, ELISA, radioimmunoassay, immunofluorescence, in vitro cell culture, double antibody sandwich method, PCR amplification and electron microscopy were used to detect the levels of peripheral blood mononuclear cells, Neutrophils, platelet function and morphology of a series of studies.