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目的探讨保留子宫动脉上行支的子宫中心体切除治疗子宫良性疾患(包括子宫肌瘤、子宫腺肌病、难治性功血)的临床价值.方法以子宫体良性疾病且无生育要求的患者行保留子宫动脉上行支的子宫中心体切除术35例为研究组,同期同样疾病行传统子宫次全切除术35例为对照组,比较两组的手术时间、术中出血量、术后性生活质量、围绝经期症状,以及术前和术后3、6月、1年检测血清性激素水平.结果研究组术中出血量、手术时间、术后月经情况与对照组比较差异无统计学意义(P >0.05),出现围绝经期症状和性生活质量下降两组比较差异有统计学意义(P 0.05),对照组术后与术前比较 E2明显降低(P <0.05),FSH 明显升高(P 0.05) on blood loss, operative time, menstruation after operation. While there is statistical significance (P 0.05), and in the control group E2 was significantly decreased postoperative (P<0.05), FSH was increased markedly (P<0.05), and HL with no significant change. Conclusions Central uterine body removal was a simple, easy and effective method with no effect on ovarian function, which can meet the patient physiological and psychological needs, who want to cure disease as wel as preserve uterus. And it is the first choice for young patients with uterine benign diseases and no fertility requirements.