七十年代以来,H_2受体阻断剂在临床上广泛应用,在治疗以胃酸增高为主要表现的疾病中发挥了重要作用,并积累了一定的经验。当前,国内外应用的H_2受体阻断剂主要为甲氰咪胍及呋喃硝胺。本文主要围绕这两种药物对消化性溃疡的疗效、剂量、副作用及预防复发等问题进行分析综述。 Since the seventies, H 2 receptor blockers have been widely used clinically and have played an important role in the treatment of diseases characterized by increased gastric acidity, and have accumulated some experience. At present, the H 2 receptor blockers used at home and abroad are mainly cimetidine and furanitramine. This article focuses on the two drugs on the efficacy of peptic ulcer, dose, side effects and prevention of recurrence and other issues were reviewed.