潜伏期硬膜外分娩镇痛对母婴影响的临床研究

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目的:探讨潜伏期硬膜外分娩镇痛对产程及母婴安全的影响。方法:符合入选标准愿接受分娩镇痛签订分娩镇痛协议书的100例初产妇进入研究组、不愿接受分娩镇痛的100例初产妇进入对照组。研究组利用0.1%罗哌卡因(新型的局部麻醉药)复合2μg/ml芬太尼(阿片类镇痛药)配成镇痛液,在宫口开2 cm时开始镇痛,先给12 ml试验量后接镇痛泵,宫口开10 cm停泵。对照组:按产科常规处理。结果:利用0.1%罗哌卡因复合2μg/ml芬太尼硬膜外分娩镇痛效果较好,但研究组使用缩宫素的比例高于对照组,差异有统计学意义(P<0.05)。分娩方式、剖宫产比例、产程时间、产后2 h出血量、新生儿1 min Apgar评分、各种不良反应等指标两组差异无统计学意义(P>0.05)。结论:潜伏期硬膜外分娩镇痛效果可靠、母婴安全。 Objective: To investigate the effects of epidural labor analgesia on labor and maternal-child safety. Methods: According to the inclusion criteria, 100 cases of primiparous women who were willing to accept analgesia for labor analgesia and entered into labor analgesia protocol were enrolled in the study group. 100 cases of primiparous women who were not willing to accept childbirth analgesia entered the control group. The research team dubbed analgesics with 0.1% ropivacaine (a new local anesthetic) in combination with 2μg / ml fentanyl (opioid analgesics) and began analgesia 2 cm apart when the cervix was opened, giving 12 ml test after the analgesic pump, cervix open 10 cm stop pump. Control group: according to obstetric routine treatment. Results: The analgesic effect of epidural analgesia with 0.1% ropivacaine combined with 2μg / ml fentanyl was better than that of the control group (P <0.05) . The mode of delivery, the proportion of cesarean section, labor time, 2 h postpartum hemorrhage, 1 minute Apgar score, various adverse reactions and other indicators of the two groups showed no significant difference (P> 0.05). Conclusion: The analgesic effect of epidural delivery is reliable and maternal and infant are safe.
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