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We report the dark matter search results obtained using the full 132 tonday exposure of the PandaⅩ-Ⅱ ex-periment,including all data from March 2016 to August 2018.No significant excess of events is identified above the expected background.Upper limits are set on the spin-independent dark matter-nucleon interactions.The lowest 90％confidence level exclusion on the spin-independent cross section is 2.2 × 10-46 cm2 at a WIMP mass of 30 GeV/c2.