泰必利Tiapride是一种含烷砜的邻茴香酰胺衍生物,可治疗顽固性头痛和各种疼痛综合征等,是一种新型神经精神安定药。国外自1974年开始用于临床。我科于1983年7月～1984年2月用泰必利(江苏淮阴制药厂试产)治疗头痛,效果满意,现报导如下: 对象和方法一、病例选择:采用抽签随机化法,对门诊成人非症状性头痛患者87例(血管性头痛54例、典型偏头痛5例、神经性头痛28例),单用泰必利治疗。另41例用安慰剂治疗。这些患者以往多数曾用过多种镇静止痛剂及抗5-HT Tiapride Tiapride is an alkane sulfonated o-anisamide derivatives, can treat intractable headache and various pain syndrome, is a new neuropsychic stabilizer. Foreign since 1974 for clinical use. Our department from July 1983 to February 1984 with tiapride (Jiangsu Huaiyin Pharmaceutical Factory trial production) treatment of headache, the effect is satisfactory, are reported as follows: Subjects and methods A case selection: randomized by lottery method, outpatient Eighty-seven adult patients with non-symptomatic headache (vascular headache in 54, typical migraine in 5 and neuropathic headache in 28) were treated with tiapride alone. The other 41 cases were treated with placebo. In the past, most of these patients had used multiple sedation analgesics and anti-5-HT