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患者女,69岁,因腹,3年余于1991年8月14日入院。3年前因腹胀在厂医务室检查发现脾大,无腹水。2年前在某医院检查脾大平脐,移动性浊音可疑,肝、肾功能正常。周围血象:白细胞12～25×10~9/L,中性粒细胞88%～95%。骨髓检查示有核细胞量增多,粒系增生活跃,以中幼粒以下阶段增生为主,少数粒细胞浆内可见少量空泡,红系增生活跃,巨核细胞数量增多,成熟淋巴细胞比例稍减低。外周血血红蛋白和血小板值在正常范围。诊断为慢性中性粒细胞白血病(CNL后患者腹胀加剧,白细胞及中性粒细胞持续增多,前者在20～
Female patient, 69 years old, due to abdominal, more than 3 years admitted to hospital on August 14, 1991. 3 years ago due to bloating in the factory clinic found spleen, no ascites. 2 years ago in a hospital to check spleen Daiping umbilical, mobility dull suspicious, liver and kidney function is normal. Peripheral blood: white blood cells 12 ~ 25 × 10 ~ 9 / L, neutrophils 88% to 95%. Bone marrow examination showed an increase in the number of nuclear cells, granulocyte hyperplasia active in the following stages of immature hyperplasia, a small number of small cytoplasm can be seen in a small number of vacuoles, erythroid hyperplasia, megakaryocyte number increased, the proportion of mature lymphocytes decreased slightly . Peripheral blood hemoglobin and platelet values in the normal range. Diagnosis of chronic neutrophilic leukemia (CNL patients exacerbated abdominal distension, white blood cells and neutrophils continued to increase, the former at 20 ~