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目的对比二甲双胍及拜糖平两种药物在2型糖尿病治疗上具有的临床疗效与安全性。方法 54例2型糖尿病患者,随机分为对照组和研究组,各27例。对照组给予二甲双胍治疗,研究组给予拜糖平治疗,对比两组患者的临床指标与副作用。结果两组的空腹血糖(FBG)、餐后血糖(PBG)、糖化血红蛋白(Hb A1c)在服药后均有显著下降(P<0.05)。两组患者服药后的各项指标比较差异无统计学意义(P>0.05)。研究组不良反应率为37.04%,对照组为44.44%,两组比较差异无统计学意义(P>0.05)。结论两种药物治疗糖尿病均有一定的疗效,不良反应率相近,临床可酌情联合用药。
Objective To compare the clinical efficacy and safety of metformin and albuterol in the treatment of type 2 diabetes mellitus. Methods 54 cases of type 2 diabetes were randomly divided into control group and study group, with 27 cases in each group. The control group was treated with metformin, and the study group was given orally administered cisplatin, comparing the clinical indexes and side effects of the two groups. Results Fasting blood glucose (FBG), postprandial blood glucose (PBG) and Hb A1c in both groups were significantly decreased after treatment (P <0.05). The two groups of patients after taking the indicators showed no significant difference (P> 0.05). Adverse reaction rate was 37.04% in the study group and 44.44% in the control group, with no significant difference between the two groups (P> 0.05). Conclusion Both drugs have certain curative effect on diabetes mellitus, with similar adverse reaction rate.