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目的:分析腹腔镜输卵管妊娠手术前后β–HCG的变化规律,探讨预防持续性输卵管妊娠发生的措施。方法:腹腔镜输卵管妊娠手术98例,其中输卵管切除63例、保守性手术35例,手术前后监测β–HCG变化,按照“(术前数值-术后数值)÷术后天数÷术前数值×100%”公式计算,分析输卵管切除术前后β–HCG下降规律。结果:术前β–HCG数值个体间变异很大,平均(20178.6±47157.2)U/L,但按照公式计算结果,个体自身下降比率为:术后第2天(42.7±1.3)%,术后第3天(28.9±2.7)%,术后第4天(23.6±0.7)%,术后第5天(19.1±0.6)%。结论:按照“(术前数值-术后数值)÷术后天数÷术前数值×100%”公式计算,再减去10%,下降速度低于此结果者作为标准,及时给予MTX治疗,对于防止持续性输卵管妊娠发生具有重要意义。
Objective: To analyze the changes of β-HCG before and after laparoscopic tubal pregnancy and to explore the measures to prevent the occurrence of persistent tubal pregnancy. Methods: Laparoscopic tubal pregnancy surgery in 98 cases, including tubal resection in 63 cases, conservative surgery in 35 cases, before and after the change of β-HCG monitoring, according to “(preoperative value - postoperative value) ÷ postoperative days ÷ preoperative value × 100% ”formula, analysis of tubal resection before and after the decline of β-HCG. Results: The preoperative β-HCG value varied greatly between individuals (20178.6 ± 47157.2 U / L), but according to the formula, the rate of individual self-descent was: 42.7 ± 1.3% on the second postoperative day, The third day (28.9 ± 2.7)%, the fourth day after operation (23.6 ± 0.7)% and the fifth day after operation (19.1 ± 0.6)%. Conclusions: MTX treatment was given in time according to the formula of “(preoperative value - postoperative value) ÷ postoperative day number ÷ preoperative value × 100%” formula, minus 10%, and the falling speed was lower than the result , For the prevention of persistent tubal pregnancy is of great significance.