帕金森氏病有否肌无力以往文献尚有争论。帕金森氏病病人常诉无力,但一般检查极少发现肌力异常。作者用一种特殊设计的肌力测试仪对21名早期帕金森氏病男性病人(平均年龄62.5岁,其中Ⅰ期17名,Ⅱ期4名)及21名无乏力主诉的男性作为对照组(平均年龄62.5岁)进行了肌力定量测试。结果表明所有病人手肌力测试均正常。两组之间握力无差别。病人两侧腕部、上肢和膝部的屈肌和伸肌的最大等张肌力都有显著降低,而肌耐力有明显增加者占测试半数。偏侧帕金森氏病中,受累侧和非受累侧的握力无区别,所有测试中,受累侧的肌力稍有降低,但两侧无统计学差别。单侧震颤与单侧肌强直者相比其握力有显著降低。震颤病人的肌力略低于平均记分,但与肌强直病人相比则无统计学 Parkinson’s disease has muscle weakness In the past the literature is still controversial. Parkinson’s disease patients often complain of weakness, but the general examination rarely found abnormal muscle strength. The authors used a specially designed muscle tester for 21 male patients with early Parkinson’s disease (mean age 62.5 years, 17 with stage I, 4 with stage II) and 21 males without complaints of malaise (control group Average age of 62.5 years old) muscle strength quantitative test. The results showed that all patients hand muscle strength test were normal. Grip between the two groups no difference. Patients on both sides of the wrist, upper limb and knee flexor and extensor maximum isosceles muscle strength was significantly reduced, while significantly increased muscle endurance accounted for half of the test. In Parkinson’s disease, there was no difference in grip strength between affected and non-affected sides. In all tests, muscle strength at affected side slightly decreased, but there was no statistical difference between the two sides. Unilateral tremor and unilateral muscle stiffness compared to its grip was significantly reduced. Tremor patients’ muscle strength was slightly lower than the mean score, but not statistically significant when compared to patients with muscle rigidity