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目的:观察甲克霉唑联合超声波臭氧雾化妇科治疗仪治疗女性念珠菌性阴道炎的临床疗效。方法:200例念珠菌性阴道炎患者采取抽签法分为观察组和对照组各100例。对照组给予甲克霉唑乳膏治疗,阴道给药,qd;观察组在对照组治疗基础上加用超声波臭氧雾化妇科治疗仪治疗,qd,15 min/次,共5次。对比两组的临床疗效和6个月复发率,同时治疗前和治疗后第1、第4周行阴道分泌物细菌培养,测定pH。结果:观察组痊愈率和总有效率分别为88%和98%,明显高于对照组的69%和82%(P<0.05)。随访6个月,观察组复发率为1.0%(1/98)明显低于对照组7.3%(6/82)(P<0.05)。治疗后,观察组阴道pH出现明显下降(P<0.05),乳酸杆菌明显增加(P<0.05);而对照组治疗前后p H和菌群数无明显变化(P>0.05)。结论:甲克霉唑加用超声波臭氧雾化妇科治疗仪治疗念珠菌阴道炎能提高治疗效果。
Objective: To observe the clinical efficacy of methicillin-azole combined with ultrasonic ozone atomization gynecological therapeutic apparatus in the treatment of Candida vaginitis in women. Methods: 200 cases of Candida vaginitis patients were divided into observation group and control group by lottery method of 100 cases. The control group was treated with clotrimazole cream, vaginal administration, qd; the observation group was treated with ultrasonic ozone atomization gynecological therapy instrument on the basis of the control group, qd, 15 min / time for 5 times. The clinical efficacy and recurrence rate at 6 months were compared between the two groups. Bacterial culture of vaginal secretions was also performed before treatment and at the first and fourth week after treatment. The pH was measured. Results: The cure rate and total effective rate in the observation group were 88% and 98% respectively, significantly higher than those in the control group (69% and 82%, P <0.05). The follow-up of 6 months, the observation group recurrence rate was 1.0% (1/98) was significantly lower than the control group 7.3% (6/82) (P <0.05). After treatment, the vaginal pH of the observation group decreased significantly (P <0.05), while that of Lactobacillus increased significantly (P <0.05). However, there was no significant change in the levels of p H and bacteria in the control group before and after treatment (P> 0.05). Conclusion: Methicillin azole plus ultrasonic ozone atomization gynecological treatment of Candida vaginitis can improve the therapeutic effect.