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本文报道了10例T细胞恶性增生病人的细胞遗传学研究结果。此外综合整理了以前报道的170例确诊为T细胞淋巴瘤的细胞遗传学所见,并绘制涉及T细胞恶性肿瘤的染色体区域和显带图。本组研究包括5例皮肤T细胞淋巴瘤,3例T细胞慢性淋巴白血病,1例T细胞前淋巴细胞白血病和1例T细胞型胚胎免疫肉瘤。除第2例10号和22号染色体简单易位之外,均发现复杂的结构和数量的克隆核型变化。染色体异常丢失数量比获得染色体的频
This article reports 10 cases of T cell malignant hyperplasia in patients with cytogenetics research results. In addition, a comprehensive review of the previously reported cytogenetics of 170 cases of T-cell lymphomas was made and the chromosomal regions and bands of T-cell malignancies were mapped. This group of studies included 5 cases of cutaneous T-cell lymphoma, 3 cases of T-cell chronic lymphocytic leukemia, 1 case of T-cell pre-lymphocytic leukemia and 1 case of T-cell type embryonal immunosarcoma. In addition to the simple translocation of chromosome 2 on chromosomes 10 and 22, both the complex structure and number of clonal karyotypes were found. The number of chromosomal abnormalities than chromosomal frequency loss