论文部分内容阅读
目的探讨血清降钙素原及C反应蛋白水平与新生儿早发型败血症相关性及其诊断价值。方法选择本科2008年6月~2012年6月出生后经血培养确诊为早发型败血症的患儿39例作为实验组,选择同期住院的非感染新生儿39例作为对照组,分别于抗生素治疗前后测定两组患儿降钙素原、超敏C反应蛋白、白细胞计数、血小板计数。结果抗生素治疗前,实验组患儿血清降钙素原、超敏C反应蛋白明显高于对照组,且差异有统计学意义(P<0.05);抗生素治疗后,实验组患儿血清降钙素原、超敏C反应蛋白明显降低,与对照组比较,差异无统计学意义(P>0.05)。结论患儿血清降钙素原、超敏C反应蛋白升高对新生儿早发型败血症有一定的诊断价值,并有助于评估疾病的治疗效果。
Objective To investigate the correlation between serum procalcitonin and C-reactive protein and neonate’s early-onset sepsis and its diagnostic value. Methods Thirty-nine children with early-onset sepsis diagnosed by blood culture from June 2008 to June 2012 were selected as the experimental group, and 39 non-infected neonates were selected as the control group before and after antibiotic treatment Two groups of children with procalcitonin, high-sensitivity C-reactive protein, white blood cell count, platelet count. Results Before treatment with antibiotics, serum procalcitonin and high-sensitivity C-reactive protein in experimental group were significantly higher than those in control group (P <0.05). After antibiotic treatment, serum calcitonin The original and hypersensitive C-reactive protein were significantly lower than that of the control group, with no significant difference (P> 0.05). Conclusion Serum procalcitonin and hypersensitive C-reactive protein in children with early onset sepsis have certain diagnostic value, and help to assess the therapeutic effect of the disease.