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目的探讨孕晚期母亲体成分、血脂水平状态与新生儿出生体重之间的关系。方法选择来我院建卡的单胎健康孕妇63例,孕前无基础疾病,未合并妊娠期高血压疾病、妊娠期肝内胆汁淤积症、口服糖耐量实验阴性。于孕晚期(孕37-38周)测得人体测量学指标、血脂指标,并用多频节段生物电阻抗分析(segmentalmulti-frequency bioelectrical im-pedance analysis,SMFBIA)测定母亲体成分,分析其与新生儿出生体重的关系。结果我院孕晚期母亲血脂水平高于正常参考值范围,胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白AⅠ(apoAⅠ)、载脂蛋白B(apoB)、脂蛋白a(Lp(a))等与新生儿出生体重之间无相关性(P>0.05);母亲体成分的指标中,上臂肌围(arm muscle circumference,AMC)、蛋白质、无机盐、脂肪量(fat mass,FM)等与新生儿出生体重之间无相关性(P>0.05);基础代谢率(basal metabolic rate,BMR)、体细胞群(body cell mass,BCM)、细胞内液(intracellular fluid,ICW)、细胞外液(extracellular fluid,ECW)、总体水(total body water,TBW)、无脂组织(fat freemass,FFM)与新生儿出生体重相关(P<0.05);FFM是对新生儿出生体重贡献最大的因素。结论体成分与血脂水平在代谢水平上紧密联系,反应了母体的营养状态,对胎儿发育产生重要影响。体成分中的FFM可能是新生儿出生体重的一个预测因子。
Objective To investigate the relationship between body composition, serum lipids and newborn birth weight in the third trimester of pregnancy. Methods Sixty-three singleton healthy pregnant women who chose to construct a card in our hospital had no underlying diseases before pregnancy, no hypertensive disorder complicating pregnancy, intrahepatic cholestasis of pregnancy and oral glucose tolerance test. In the third trimester of pregnancy (37-38 weeks of gestation), the anthropometric indexes and blood lipid indexes were measured, and the body composition was determined by segmentalmulti-frequency bioelectrical im-pedance analysis (SMFBIA) The relationship between birth weight. Results The level of serum lipids in the third trimester of pregnancy in our hospital was higher than the normal reference value. The levels of cholesterol, triglyceride, HDL-C, LDL-C, There was no correlation between newborn birth weight and apoAⅠ, apoB and Lp (a) (P> 0.05). Among the indexes of mother’s body composition, the upper arm muscle There were no correlations between AMC, protein, inorganic salt, fat mass (FM) and birth weight (P> 0.05). The basal metabolic rate (BMR) Body cell mass (BCM), intracellular fluid (ICW), extracellular fluid (ECW), total body water (TBW), fat free mass (FFM) And birth weight (P <0.05). FFM was the most contributory factor of newborn birth weight. Conclusion Body composition and lipid levels are closely related to the level of metabolism, which reflects the nutritional status of the mother and has an important impact on fetal development. FFM in body composition may be a predictor of newborn birth weight.