论文部分内容阅读
生育期子宫内膜异位症(EMs)患者最常选用的手术方式是保留生育功能手术,作为一种雌激素依赖性疾病,EMs在保留生育功能手术后复发率极高,如何有效地预防保留生育功能手术后EMs病灶及症状的复发是临床工作中急需解决的难题。目前临床中主要的预防措施分为短期预防和长期预防(≥6个月)。短期预防以促性腺激素释放激素激动剂(GnRH-a)(3~6个周期)的应用最为广泛,但停药后对远期复发率无明显改善。长期预防措施主要包括短效口服避孕药或者左炔诺孕酮宫内节育系统的单药方案以及与GnRH-a的联合方案。本文就EMs患者在保留生育功能手术之后采取不同的治疗措施预防EMs临床症状和病灶的复发分别进行综述。
Reproductive endometriosis (EMs) in patients with the most commonly used surgical approach is to retain fertility surgery, as an estrogen-dependent disease, EMs recurrence rate after retention fertility surgery, how to effectively prevent reservations The recurrence of EMs lesions and symptoms after fertility surgery is an urgent problem to be solved in clinical work. The main clinical preclinical measures are divided into short-term prevention and long-term prevention (≥6 months). Short-term prophylaxis with gonadotropin-releasing hormone agonist (GnRH-a) (3 to 6 cycles) is the most widely used, but no significant improvement in the long-term recurrence rate after withdrawal. Long-term preventive measures include short-acting oral contraceptives or levonorgestrel intrauterine system of single-drug regimens and the combination with GnRH-a program. In this paper, EMs patients with reproductive function retention after taking different treatment measures to prevent the clinical symptoms of EMs and the recurrence of lesions were reviewed.