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目的探讨胃黏膜保护剂联合质子泵抑制剂对胃溃疡患者愈合质量的影响。方法随机选取医院收治的胃溃疡患者80例,按随机数字表法分为研究组和对照组,各40例。研究组患者予胃黏膜保护剂联合质子泵抑制剂治疗,对照组患者予单纯质子泵抑制剂治疗。结果研究组患者的总有效率为97.50%,显著高于对照组的67.50%(P<0.05),溃疡愈合质量显著优于对照组(P<0.05),复发率显著低于对照组(P<0.05);两组不良反应发生率比较,无统计学差异(P>0.05)。结论胃黏膜保护剂联合质子泵抑制剂能有效提升胃溃疡患者的愈合质量。
Objective To investigate the effect of gastric mucosal protective agent and proton pump inhibitor on the healing of gastric ulcer patients. Methods Eighty patients with gastric ulcer were selected randomly from the hospital. The patients were divided into study group and control group according to random number table. Patients in the study group were treated with gastric mucosal protective agent and proton pump inhibitor, and patients in control group were treated with simple proton pump inhibitor. Results The total effective rate of the study group was 97.50%, which was significantly higher than that of the control group (67.50%, P <0.05). The healing quality of the ulcer was significantly better than that of the control group (P <0.05), and the recurrence rate was significantly lower than that of the control group (P < 0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion Gastric mucosal protective agent combined with proton pump inhibitor can effectively improve the quality of healing of gastric ulcer patients.