甲状腺功能减退症(甲减)与乳溢是一种少见的内分泌疾病。1956年Jackson首先报道1例原发性甲减伴乳溢的病例。本病可同时并有闭经,称甲减-乳溢-闭经综合征。随着内分泌激素的放射免疫测定和CT扫描技术的广泛开展,以及对甲减症的特殊临床表现乳溢、闭经的重视和发病机理的研究,本病的病例报道也逐渐增多,对于本病的病因、病理生理、临床特点、病情发展、预后及治疗,也随之逐渐深入了解而渐趋明朗化。 Hypothyroidism (hypothyroidism) and milk overflowing is a rare endocrine disease. Jackson first reported in 1956 a case of primary hypothyroidism associated with galactorrhea. The disease can be accompanied by amenorrhea, hypothyroidism - milk overflow - amenorrhea syndrome. With the endocrine hormone radioimmunoassay and CT scanning technology is widely carried out, as well as the special clinical manifestations of hypothyroidism, milk overflow, amenorrhea attention and pathogenesis research, the case of this disease has gradually increased, for the disease Etiology, pathophysiology, clinical features, disease progression, prognosis and treatment, but also gradually understand and gradually become clearer.