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两年多以前,少数几个欧洲及北美中心将绒毛取材(CVS)作为一种产前诊断方法。本次会议的目的是复审当前对CVS危险的评价。四个中心已有500例以上的经验,另外五个有100例以上的经验。当前使用的取材方法主要有四种。将使用相同器械和操作标准很相似的3个中心1880例以上的经验综合起来,可以与其他资料作比较,取材成功率(平均98.8%,范围98～99.5%)及流产率(平均2.4%,范围1.9～3%)很相似。校正后;确因CVS的流产发生率不大于0.7%。至少已确定有四种因素影响流产率:(1)操作人员的技术能力:如已具有CVS的经验,则流产率下降。(2)要求标本的数量:如一次取够,则流产
More than two years ago, a few centers in Europe and North America used villus harvesting (CVS) as a prenatal diagnostic method. The purpose of this meeting is to review the current assessment of the dangers of CVS. The four centers have more than 500 experience and the other five have more than 100 experience. There are currently four main ways to draw material. A total of 1880 or more experiences using the same instrument and three centers with similar standards of operation were summarized and compared to other data with success rates (mean 98.8%, range 98-99.5%) and miscarriage rates (average 2.4% Range 1.9 ~ 3%) is very similar. After correction; indeed, the incidence of miscarriage of CVS is not more than 0.7%. At least four factors have been identified that affect the abortion rate: (1) Technical skills of the operator: If already experienced with CVS, abortion rates decline. (2) the number of specimens required: If enough time to take, the abortion