论文部分内容阅读
心力衰竭患者往往伴有容量负荷过重,利尿则是一线治疗。血管加压素V2受体拮抗剂托伐普坦口服可促进自由水的排出而减轻容量负荷。通过检索PubMed、Science Direct数据库,对托伐普坦治疗心力衰竭的研究情况进行综述。“,”Patients with heart failure often develop volume overload.Diuretics are the first-line therapy.Tolvaptan is an orally specific antagonist of the V2 receptor that enhances the excretion of free water to treat volume overload.Database of PubMed and Science Direct were searched to review the studies of tolvaptan on treating heart failure.