论文部分内容阅读
目的对传统中药华中五味子中的化学成分进行初步研究。方法运用多种色谱方法分离纯化,通过现代波谱解析技术(如NMR和MS等)和理化数据的文献对照,鉴定结构。结果与结论从华中五味子中分离得到了10个化合物,分别鉴定为五味子酚(schisanhenol,1)、五味子酯乙(schisantherin B,2)、chicanine(3)、pregomisin(4)和甘五酸(schizandronic acid,5)、去氧五味子素(6)、前戈米辛(7)、内消旋二氢愈创木脂素(8)、五味子酯甲(9)、戈米辛P顺芷酸酯(10)。首次从该植物中分离得到化合物前戈米辛(7)。
Objective To study the chemical constituents of Schisandra chinensis in traditional Chinese medicine. The method was isolated and purified by a variety of chromatographic methods. The structure was identified by literature comparison of modern spectroscopic analytical techniques (such as NMR and MS) and physical and chemical data. RESULTS AND CONCLUSION Ten compounds were isolated from Schisandra chinensis, identified as schisanhenol (1), schisantherin B (2), chicanine (3), pregomisin (4) and schizandronic (5), deoxycholate (6), pregamexin (7), meso dihydroguguaconal (8), schisandrins A (9) (10). For the first time, Gomisin (7) was isolated from this plant.