子宫内膜异位症术后3种药物治疗成本-效果及不良反应分析

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目的评价3种不同药物治疗子宫内膜异位症的疗效和成本。方法子宫内膜异位症术后患者共131例,分为3组,A组42例,皮下注射达菲林;B组46例,口服孕三烯酮;C组43例,口服丹那唑。比较3组患者成本-效果比和不良反应的差异。结果 A、B、C三方案成本分别为12699元、2337.24元、1896.6元,总有效率分别为95.24%、93.48%、88.37%。成本-效果比分别为133.43、25.00、22.03。A组不良反应发生率较低。结论 3种治疗方案,C方案成本-效果比最低,显示C方案最经济有效。A方案较少引起阴道异常出血和体重增加的不良反应。 Objective To evaluate the efficacy and cost of three different drugs in the treatment of endometriosis. Methods A total of 131 cases of postoperative patients with endometriosis were divided into 3 groups, 42 cases in group A were injected subcutaneously with dipyridamole; 46 cases in group B were treated with gestrinone; 43 cases in group C were treated with danazol. The differences of cost-effectiveness ratio and adverse reactions between the three groups were compared. Results The costs of A, B and C programs were 12699 yuan, 2337.24 yuan and 1896.6 yuan respectively, with the total effective rates of 95.24%, 93.48% and 88.37% respectively. Cost-effectiveness ratio was 133.43,25.00,22.03. A group of adverse reactions were lower. Conclusions The cost-effectiveness ratio of three kinds of treatment options and the cost-effectiveness ratio of option C is the lowest, which shows that option C is the most economical and effective. A program less likely to cause abnormal vaginal bleeding and weight gain adverse reactions.
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