喉上神经阻滞和／或环甲膜穿刺气管内给药表面麻醉降低气管插管的应激反应是临床常用的方法［１～４］。但两者结合的药代动力学研究未见报道。本文拟就此加以研究。１　资料与方法择期全麻手术的病人８例，ＡＳＡＩ～ＩＩ级，无心、肺、脑、肝、肾功能障碍，呼吸道无炎症。男 Upper thoracic nerve block and / or cricothyroid membrane tracheal intratracheal administration of anesthesia to reduce the stress response of tracheal intubation is commonly used in clinical practice [1 ~ 4]. However, the combination of the two pharmacokinetic studies have not been reported. This article is about to be studied. 1 Materials and Methods Elective anesthesia in patients with 8 cases, ASAI ~ II level, no heart, lung, brain, liver and kidney dysfunction, respiratory inflammation. male