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目的观察一次性大剂量干扰素联合阿昔洛韦等治疗中老年带状疱疹的疗效。方法将100例患者随机分为两组,治疗组50例用重组干扰素300万单位肌注,口服阿昔洛韦、维生素B1、消炎痛,对照组50例除不用干扰素外,余同治疗组。结果治疗组在止痛时间、止泡时间、结痂时间均显著短于对照组,差异有统计学意义(t=6.430~8.556,P<0.01)。结论大剂量干扰素联合阿昔洛韦等治疗中老年带状疱疹起效快、疗程短、疗效好。
Objective To observe the efficacy of one-time high-dose interferon combined with acyclovir in the treatment of middle-aged and elderly herpes zoster. Methods 100 patients were randomly divided into two groups, the treatment group of 50 patients with recombinant interferon 3 million intramuscular injection of acyclovir, vitamin B1, indomethacin, the control group of 50 patients without interferon, Yu Tong treatment group. Results The pain relief time, defatting time and scab time of the treatment group were significantly shorter than those of the control group (t = 6.430-8.556, P <0.01). Conclusion High-dose interferon combined with acyclovir and other treatment of middle-aged and elderly herpes zoster onset fast, short course, good curative effect.