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目的 探讨不同低剂量米非司酮用于紧急避孕的临床效果、副作用及对月经的影响。方法 为无防护或避孕套使用失败性生活后 72h内的 15 7例月经规则妇女提供紧急避孕服务。随机分为A组 ( 79例 )及B组 ( 78例 ) ,分别一次顿服米非司酮 5 0mg及 2 5mg。结果 按Dixon法计算避孕有效率分别为 10 0 %及 61% ,两组间比较差异有显著性 (P <0 0 5 )。服药后的副作用及对月经周期、月经量的影响 ,两组间差异无显著性 (P >0 0 5 )。结论 米非司酮 5 0mg用于紧急避孕较 2 5mg更佳 ,更有希望成为首选的紧急避孕方剂。
Objective To investigate the clinical effects, side effects and the effect on menses of different low dose mifepristone for emergency contraception. The method was to provide emergency contraception services to 15 7 menstruating women within 72 hours after failure of sexual life on condoms or condoms. Randomly divided into A group (79 cases) and B group (78 cases), respectively, a dose of mifepristone 50mg and 25mg. Results According to the Dixon method, the effective rates of contraception were 100% and 61%, respectively. There was significant difference between the two groups (P <0.05). After taking the side effects and menstrual cycle, menstrual volume, no significant difference between the two groups (P> 0.05). Conclusion 50 mg of mifepristone is better than 25 mg for emergency contraception and more promising as the first choice for emergency contraception.