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本文报告了51例黄疸病人测定血中癌胚抗原(CEA)浓度的结果,证明本项试验可用于区分良性和恶性黄疸。全组病例同时还作了肝功试验,X线摄影,超声波检查,内窥镜逆行胆道造影,但这些检查对于鉴别良性和恶性黄疸尚不够满意。51例剖腹探查结果,17例良性黄疸中包括10例毛细胆管炎,其中16例(94%)血中癌胚抗原浓度小于或等于5.0ng/ml;仅1例大于5.0ng/ml,而血中癌胚抗原浓度大于5.0ng/ml病例中,96%为恶性病变。良性黄疸病例的平均血胆红素浓度11.2mg/dl,恶性病例组则为12.1
This article reports the results of 51 patients with jaundice who measured CEA concentrations in the blood, demonstrating that this test can be used to distinguish between benign and malignant jaundice. The whole group of cases also had liver function tests, X-ray photography, ultrasound examinations, and endoscopic retrograde cholangiography. However, these examinations were not satisfactory for the identification of benign and malignant jaundice. In 51 cases of exploratory laparotomy, 17 cases of benign jaundice included 10 cases of capillary cholangitis, of which 16 cases (94%) had a carcinoembryonic antigen concentration of less than or equal to 5.0 ng/ml; only 1 case was greater than 5.0 ng/ml, while blood In cases with a carcinoembryonic antigen concentration greater than 5.0 ng/ml, 96% were malignant lesions. The average blood bilirubin concentration in patients with benign jaundice was 11.2 mg/dl, and that in malignant cases was 12.1.